𝘕,𝘕'-Diisopropyl-𝙊-𝙩𝙚𝙧𝙩-butyl isourea: an efficient reagent for 𝙩𝙚𝙧𝙩-butyl esters synthesis

tert-Butyl esters are commonly used as protecting group of carboxylic acids in multi-step synthesis, especially with amino acids, peptides and natural products. [1] The importance of this relatively hindered protecting group is well established.

Full article: Preparation and Applications of 4-Methoxybenzyl Esters in Organic Synthesis

Organic Syntheses Procedure

Full article: Preparation and Applications of 4-Methoxybenzyl Esters in Organic Synthesis

Organic Syntheses Procedure

Organic Syntheses Procedure

Synthesis of 1-(tert-Butyl) 4-Methyl (1R,2S,4R)-2-Methylcyclohexane-1,4-dicarboxylate from Hagemann's tert-Butyl Ester for an Improved Synthesis of BMS-986251

Microwave-Assisted Ester Formation Using O-Alkylisoureas: A Convenient Method for the Synthesis of Esters with Inversion of Configuration

Alkylating Reagents Containing Phosphoric Ester Groups for Prodrug Design

Bacterial conversion of tert-butyl compounds. (A) Proposed pathways

Scheme 2. Synthesis of tert-butyl

Synthesis of 3(2H)‐Furanones: A Review - Omanakuttan - 2021 - European Journal of Organic Chemistry - Wiley Online Library